Medical Grand Rounds

Spring 2013

Thursdays, 12:00 PM
Kontos Medical Sciences Building Auditorium

January | February | March | April | May | June

Podcasts on select lectures may be accessed from VCU’s iTunes University and requires download of iTunes from Apple’s website and a VCU eID to access. PowerPoint presentations also require a VCU eID to access.

January

Jan. 3

HAPPY HOLIDAYS!
No Grand Rounds This Week.

Jan. 10

Renal Artery Ablation for Refractory Hypertension

George W. Vetrovec, M.D.
Kimmerling Professor of Medicine
Director, Adult Cardiac Catheterization Laboratory
VCU Pauley Heart Center
Department of Internal Medicine
VCU Medical Center

  • Learning Objectives:
  • Discuss the proposed mechanism for treatment effect
  • Describe the preliminary result
  • List other potential uses of this technology

This presentation is provided in video and audio forms below:
Video | Podcast

Jan. 17

Exploring Frontiers in Cancer Immunotherapy: A Stem Cell Transplant Perspective

Amir Toor, MD
Associate Professor,
Division of Hematology, Oncology, and Palliative Care
VCU Massey Cancer Center
Department of Internal Medicine
VCU Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Recognize allogeneic stem cell transplant as an immunotherapeutic modality
  • Recognize the value of mathematics in deciphering complex biological phenomenon such as immune response
  • Recognize the value of epigenetic modification in inducing adaptive immune response against cancers

This presentation is provided in video and audio forms below:
Video | Podcast

Jan. 24

Clinicopathological Conference

Daniel Grinnan, MD
Associate Professor of Medicine
Division of Pulmonary and Critical Care Medicine
Department of Internal Medicine
VCU Medical Center

The CPC Protocol for this presentation can be found here.

  • Following this Grand Rounds presentation, participants will be able to:
  • Recognize the etiologies and diagnosis from the clinicopathologic case presented
  • Observe an experienced clinician's diagnostic reasoning process

This presentation is provided in video and audio forms below:
Video | Podcast

Jan. 31

Hypereosinophilic Syndrome(s)

Larry Schwartz, MD, PhD
Charles & Evelyn Thomas Professor of Medicine
Chair of Division of Rheumatology, Allergy, and Immunology
Department of Internal Medicine
VCU Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Better understand the myelocytic, lymphocytic and idiopathic types
  • Understand current diagnostic criteria
  • Recognize various clinical presentations
  • Increase familiarity with therapeutic interventions

This presentation is provided in video and audio forms below:
Video | Podcast

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February

Feb. 7

Hemostasis in Acute and Chronic Liver Disease

R. Todd Stravitz, MD
Professor of Medicine
Medical Director of Liver Transplantation
Division of Gastroentrology, Hepatology and Nutrition
Department of Internal Medicine
VCU Medical Center

  • Learning Objectives for this presentation:
  • Improve understanding of global hemostasis in patients with liver disease
  • Delineate mechanisms of maintaining hemostatic equilibrium in patients with liver disease
  • Identify indications and relative contraindications for pro-hemostatic factor repletion in patients with liver disease

This presentation is provided in video and audio forms below:
Video | Podcast

Feb.14

The Evolution of Medical Education

Kelley Skeff, MD, PhD
Professor of Medicine
Vice Chair for Educational Programs
Co-Director, Standford Faculty Development Center for Medical Teachers
Stanford University

  • Following this Grand Rounds presentation, participants will be able to:
  • Apply a scheme to analyze prior and current medical education
  • Define areas that deserve more emphasis by the institutions
  • Define areas for increased emphasis in one's own teaching

This presentation is provided in video and audio forms below:
Video | Podcast

Feb. 21

Social Media and Healthcare: What is it, and why should I care?

Mark Ryan, MD, FAAFP
Assistant Clinical Professor
Department of Family Medicine
Medical Director, International/Inner City/Rural Preceptorship (I2CRP)
VCUHS

  • Following this Grand Rounds presentation:
  • Participants will be able to define social media.
  • Participants will identify five major forms of social media and discuss differences between them.
  • Participants will explain potential benefits and limits of social media use by healthcare students and professionals.
  • Participants will identify potential uses for social media in medical education.

This presentation is provided in video and audio forms below:
Video | Podcast

Feb. 28

Inpatient Management of Medical and Surgical Patients with Type 2 Diabetes

Guillermo Umpierrez, MD
Professor of Medicine
Section Head, Endocrinology and Diabetes
Grady Health System
Emory University

  • Learning Objectives for this presentation:
  • Discuss the relationship between glycemic control and clinical outcomes in medical and surgical patients in a non-ICU setting.
  • Outline strategies for achieving reasonable, achievable, and safe glycemic targets from admission to discharge.
  • Review updated recommendations for the management of hyperglycemia in general (non-ICU) medicine and surgical patients.

This presentation is provided in video and audio forms below:
Video | Podcast

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March

Mar. 7

Critical Care Ultrasound: Imaging in the Trenches

Seth Koenig, MD
Associate Professor of Medicine
Associate Director, Medical Intensive Care Unit
North Shore LIJ Health System

  • Following this Grand Rounds presentation, participants will be able to:
  • Define point of care ultrasonography
  • Explain what role point of care ultrasound plays in the intensive care unit
  • Know what training is required to perform critical care ultrasound

This presentation is provided in video and audio forms below:
Video | Podcast

Mar. 14

Clinicopathological Conference

Amit Bharara, MD
Imran Farooq, MD
Matthew Kappus, MD
Jeremy Turlington, MD, MPH

Click here for the CPC Protocol

  • Following this Grand Rounds presentation, participants will be able to:
  • Recognize the etiologies and diagnosis from the clinicopathologic case presented
  • Observe an experienced clinician's diagnostic reasoning process

This presentation is provided in video and audio forms below:
Video | Podcast

Mar. 21

Hand Hygiene: Thinking Outside The Box

Michael B. Edmond, MD, MPH, MPA
Richard P. Wenzel, MD, MSc Professor of Medicine
Division of Infectious Diseases
Department of Internal Medicine
VCU Medical Center

  • Learning Objectives for this Presentation:
  • To view hand hygiene in an historical context
  • To critically examine why healthcare workers are noncompliant with hand hygiene
  • To compare and contrast hand hygiene with other health-related behaviors

This presentation is provided in video and audio forms below:
Video | Podcast

Mar. 28

• Annual Galen Wampler Lecture •
The Massey Cancer Center Solid Tumor Translational Research Program: From Bench to Bedside

Andrew Poklepovic, MD
Assistant Professor
Division of Hematology, Oncology and Palliative Care
Developmental Therapeutic, Massey Cancer Center
Department of Internal Medicine
VCU Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Understand the basic design of a Phase I Clinical Trial
  • Review terms and methods used for monitoring toxicity and assessing response
  • Discuss adaptive design strategies
  • Better understand ongoing clinical trials at MCC, including the basic science component

This presentation is provided in video and audio forms below:
Video | Podcast

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April

Apr. 4

Cardiac Sarcoidosis

Jordana Kron, MD
Assistant Professor of Medicine
Division of Cardiology
VCU Pauley Heart Center
Department of Internal Medicine
VCU Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Understand the heterogeneous clinical presentations of Cardiac Sarcoidosis (CS)
  • Understand the roles different imaging modalities play in the diagnosis of CS
  • Identify risk factors for sudden cardiac death in patients with CS

This presentation is provided in video and audio forms below:
Video | Podcast

Apr. 11

Why Is It so !*$# Difficult to Lose Weight!

James R. Levy, MD
Professor of Medicine
Division of Endocrinology & Metabolism
VCU Medical Center
Hunter Holmes McGuire VA Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Demonstrate evidence for a weight set point
  • Explain the epidemic of obesity in the context of the set point
  • Understand the physiological reasons for energy expenditure and intake homeostasis.
  • Demonstrate the characteristics of the rare patient with successful medical weight loss.

This presentation is provided in video and audio forms below:
Video | Podcast

Apr. 18

Modulating Inflammation to Treat Acute and Chronic Organ Failure

H. David Humes, MD
Professor of Medicine
University of Michigan

  • Learning Objectives:
  • Importance of inflammation in organ dysfunction
  • Methods of immunomodulate excessive inflammation
  • Importance in heart, kidney, lung, brain injury

This presentation is provided in video and audio forms below:
Video | Podcast

Apr. 25

Understanding Inflammatory Bowel Disease Through Genetics

Steven R. Brant, M.D.
Associate Professor of Medicine
Director, Meyerhoff Inflammatory Bowel Disease Center
Director, Meyerhoff IBD Genetics Laboratory
Johns Hopkins University School of Medicine
Joint Appointment, Bloomberg School of Public Health

  • Following this Grand Rounds presentation, participants will be able to:
  • Describe evidence for genetic and environmental etiologies for inflammatory bowel disease
  • Identify classes of genes that are associated with development of inflammatory bowel disease
  • Describe similarities and differences in the genetic risks for Crohn’s disease and ulcerative colitis
  • Define how genetic variations influence the expression and course of Crohn’s disease
  • Describe evidence that the dysfunction of immunity to microbes may in part be responsible for inflammatory bowel disease

This presentation is provided in video and audio forms below:
Video | Podcast

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May

May 2

• Resident Research Presentations •

Progressive Multifocal Leukoencephalopathy (PML) with Rituximab: The High Cost of Therapy
Michele Sundar, MD (PGY-2)

  • Learning Objectives:
  • Review the clinical and radiographical presentation of Progressive Multifocal Leukoencephalopathy
  • Review how to diagnose Progressive Multifocal Leukoencephalopathy
  • Discuss prognosis, current and future treatments

Synergestic Interactions between Carflizomib and Selective HDAC6 Inhibitor (ACY1215) in DLBCL
Jawad Al-Khafaji, MD (PGY-2)

  • Learning Objectives:
  • Assess the degree of synergy between 2nd generation proteasome inhibitor (Carfilzomib) and selective HDAC6 snhibitor (ACY1215) in DLBCL
  • Investigate the cellular mechanisms behind this synergy

Outcomes of Patients with Iodinated Contrast Dye Allergy Undergoing Diagnostic Angiography and Percutaneous Intervention
Wendy Bottinor, MD (PGY-2)

  • Learning Objectives:
  • Review adverse reactions to contrast and outcomes in patients with a known allergy

Admission Mean Platelet Volume and Outcome in Acute Liver Failure
Thure Caire, MD (PGY-3)

  • Learning Objectives:
  • Explain Mean Platelet Volume (MPV) and it's importance
  • Discuss how MPV can be used in the treatment of Acute Liver Failure

This presentation is provided in video and audio forms below:
Video | Podcast

May 9

Clinicopathologic Conference

Bennett Lee, MD, MPH
Assistant Professor of Internal Medicine
Division of General Medicine
Department of Internal Medicine
VCU Medical Center

Click here to view the CPC Protocol

  • Following this Grand Rounds presentation, participants will be able to:
  • Recognize the etiologies and diagnosis from the clinicopathologic case presented
  • Observe an experienced clinician's diagnostic reasoning process

This presentation is provided in video and audio forms below:
Video | Podcast

May 16

Cardiovascular Disease in Diabetes: Mechanisms, Controversies and Best Practices

Jerry L. Nadler, MD, FACP, FAHA, FACE
Mansbach Professor of Medicine
Chair of Internal Medicine
Eastern Virginia Medical School

  • Following this Grand Rounds presentation, participants will be able to:
  • Understand the mechanisms of the growing epidemic of diabetes
  • Discuss the risks of CV disease in pre-diabeties and diabetic states
  • Clarify the role of glucose compared to other risk factors
  • Understand best treatments to reduce heart disease based on current knowledge and future research

This presentation is provided in video and audio forms below:
Video | Podcast

May 23

The Rebirth of Primary Care

Andrew Morris-Singer, MD
President and Principal Founder
Primary Care Progress

  • Following this Grand Rounds presentation, participants will be able to:
  • Understand how primary care delivery and training are being transformed and some of the characteristics underlying new models.
  • Describe the various stakeholders in our healthcare system who are now in support of primary care and why their support is so robust

This presentation is provided in video and audio forms below:
Video | Podcast

May 30

MEDICINE AND SURGERY CONFERENCE
[ Special Time & Location ]
Sanger Hall
7:00 AM - 8:00 AM

Stephanie A. Call, MD, MSPH
Associate Professor of Medicine
VCU Medical Center

Brian Kaplan, MD
Professor of Surgery
VCU Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Identify specifics of a case requiring multi-disciplinary intervention and coordination of care.
  • Explain factors which make the case complex and challenging.
  • Outline steps to improve outcome and the quality of patient care for similar cases.

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June

June 6

Peripheral Arterial Disease: An Underrecognized Cardiovascular Epidemic

Ranjith Shetty, MD
Assistant Professor of Medicine
Division of Cardiology
Department of Internal Medicine
VCU Medical Center

  • Following this Grand Rounds presentation, participants will be able to:
  • Discuss the risk factors for peripheral arterial disease.
  • Describe the symptoms and assessment of peripheral arterial disease.
  • Evaluate risks and benefits of therapies for peripheral arterial disease.

June 13

• Annual William G. Blackard Lecture •
Calcium - How Much?

Bess Dawson-Hughes, MD
Director, Bone Metabolism Laboratory,
USDA Human Nutrition Research Center on Aging
Professor of Medicine, Tufts University

  • Following this Grand Rounds presentation, participants will be able to:
  • Know the basis for determining the recommended calcium intake.
  • Review and assess recent evidence concerning safety of calcium supplementation.
  • Consider whether the requirement for calcium is dependent upon vitamin D status.
  • Define a balanced approach to meeting the calcium requirement safely.

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