Research

VCU’s Division of Pulmonary Disease and Critical Care Medicine is conducting critically important active ongoing research projects involving clinical and basic science. Division research faculty are engaged in intricate probing of pressing mysteries such as acute Lung Injury and critical illness, Pulmonary Hypertension, and hyperlipidemia with its accompanying vascular disease. Research is supported by grants from the National Institutes of Health, the American Heart Association and the American Lung Association.

Clinical Investigation Includes:

  • Treatment interventions for Lung injury, sepsis and organ failure
  • Delirium and sedation practices in critically ill patients
  • Novel treatments for asthma
  • New pharmacologic treatments for Pulmonary Hypertension.
  • Chronic obstructive pulmonary disease

The Division is participating in national clinical trials for sepsis, pneumonia, acute respiratory distress syndrome.

Basic Research Includes:

  • Mechanisms of lipid peroxidation and cholesterol ester hydrolysis in coronary artery plaques and in diabetes
  • Molecular control of inflammation in sepsis and its mediation by ascorbic acid.
  • Molecular pathogenesis of ischemia reperfusion injury
  • Molecular control of antioxidant injury in endothelial cells
  • Molecular control of lung water through sodium channels
  • Molecular mechanisms of development of pulmonary hypertension